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Created with Raphaël 2.1.0 04.05.2020 Formal examination (assignment of filing date) 29.05.2020 Preliminary examination 20.07.2020 Establishment of the national regular filing 20.07.2020 Substantive examination 30.11.2021 Publication of the application (A2) 28.02.2022 Publication of the decision of grant (B1) 31.08.2022 Completion of the opposition filing period 30.09.2022 Issuance of patent (C1) 04.04.2025 04.05.2025 Valid until 04.05.2026 Payment of maintenance fee 04.05.2040 Patent expiration date

Patent in force


(11)Number of the document4792
(21)Number of the applicationa 2020 0034
(22)Filing date of the application2020.05.04
 Date of filing the request for examination (de fond) 04.05.2020
(71)Name(s) of applicant(s), code of the countryINSTITUTUL DE CHIMIE, MINISTERUL EDUCAŢIEI ŞI CERCETĂRII, MD; KATHOLIEKE UNIVERSITEIT LEUVEN, BE; UNIVERSITÄT BERN, CH;
(72)Name(s) of inventor(s), code of the countryKULCITKI Veaceslav, MD; GIRBU Vladilena, MD; PRUTEANU Elena, MD; RENAUD Philippe, CH; DAELEMANS Dirk, BE; UNGUR Nicon, MD;
(73)Name(s) of owner(s), code of the countryINSTITUTUL DE CHIMIE, MINISTERUL EDUCAŢIEI ŞI CERCETĂRII, MD; KATHOLIEKE UNIVERSITEIT LEUVEN, BE; UNIVERSITÄT BERN, CH;
(54)Title of the invention(16R)-Spiro[pyrrolidine-2´,16-ent-17-norkauran]-19-oic acid methyl ester with selective cytotoxic activity
(13)Kind-of-document code
C1, BOPI 09/2022
B1, BOPI 02/2022
A2, BOPI 11/2021
(51)International Patent Classification C07D 209/96 (2006.01); C07C 61/125 (2006.01); A61K 31/015 (2006.01); A61K 31/403 (2006.01); A61P 35/00 (2006.01);
(19)CountryMD
(41)Date of publication of the application2021.11.30
(45)Date of publication of patent granting decision:2022.02.28
(47)Date of issuance of patent2022.09.30
(74)Patent attorneyJOVMIR Tudor, Str. Miorita nr. 5, bl. 2, ap. 19, MD-2028, Chişinău, Republica Moldova
 Substantive examiner(s)LEVIŢCHI Svetlana
 Payment for maintenance up to the date2025.05.04
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