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Created with Raphaël 2.1.0 18.11.2022 Formal examination (assignment of filing date) 22.12.2022 Preliminary examination 09.02.2023 Establishment of the national regular filing 10.02.2023 Substantive examination 31.05.2024 Publication of the decision of grant (B1) 30.11.2024 Completion of the opposition filing period 31.12.2024 Issuance of patent (C1) 03.04.2025 18.11.2027 Valid until 18.11.2028 Payment of maintenance fee 18.11.2042 Patent expiration date

Patent in force


(11)Number of the document4893
(21)Number of the applicationa 2022 0050
(22)Filing date of the application2022.11.18
 Date of filing the request for examination (de fond) 18.11.2022
(71)Name(s) of applicant(s), code of the countryINSTITUTIA PUBLICA UNIVERSITATEA DE STAT DIN MOLDOVA, MD;
(72)Name(s) of inventor(s), code of the countryKULCIŢKI Veaceslav, MD; UNGUR Nicon, MD; GRINCO Marina, MD; BUOMMINO Elisabetta, IT; LEMBO Francesca, IT;
(73)Name(s) of owner(s), code of the countryINSTITUTIA PUBLICA UNIVERSITATEA DE STAT DIN MOLDOVA, MD;
(54)Title of the inventionUse of ent-gomeroylguanidine and ent-13-epigomeroylguanidine as compounds with antimicrobial properties and synergistic effect in combination therapy
(13)Kind-of-document code
C1, BOPI 12/2024
B1, BOPI 05/2024
(51)International Patent Classification C07D 311/78 (2006.01); C07C 279/22 (2006.01); A61K 31/35 (2006.01); A61K 31/155 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01);
(19)CountryMD
(45)Date of publication of patent granting decision:2024.05.31
(47)Date of issuance of patent2024.12.31
 Substantive examiner(s)LEVIŢCHI Svetlana
 Payment for maintenance up to the date2027.11.18
 Change of the applicant
Nr. şi data deciziei:7926, 2023.06.28
Datele iniţiale:INSTITUTUL DE CHIMIE, MEC, MD str. Academiei nr. 3, MD-2028, Republica Moldova
Datele finale:INSTITUŢIA PUBLICĂ UNIVERSITATEA DE STAT DIN MOLDOVA, MD Str. A. Mateevici nr. 60, MD-2009, Chişinău, Republica Moldova
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/inventions/details/a 2022 0050